Ophthalmic evaluation of drug-resistant tuberculosis patients taking linezolid as oral longer anti-tuberculosis regime
نویسندگان
چکیده
Aim: To document ocular toxicity if any in drug-resistant tuberculosis patients taking linezolid as an oral longer regime. Study and Design: Hospital-based Observational study. Methods Material: The study was carried out tertiary health care from January 2021- October 2022. A total of 94 participants above 18 years age who were diagnosed with Linezolid had pre-treatment best-corrected visual acuity (BCVA) 6/6 N6 normal color vision included the Patients called on follow-up 2nd, 4th, 6th months post-Linezolid therapy, BCVA, vision, anterior segment examination, dilated fundus examination done documented. Results: Out 45 males 49 females. mean 27.41±9.22. We observed one patient developed a diminution changes optic disc edema second month other also came neuropathy sixth follow-up. third nonsignificant RPE without vision. Conclusion: Ocular three cases form Optic Neuropathy, edema, amongst participants. In our after withdrawal reverted to normal. highlights importance regular ophthalmic long-term therapy.
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European Union. Stockholm, ECDC, 2008. Available from: http://ecdc.europa.eu/en/publications/Publications/0803_ SPR_TB_Action_plan.pdf 5 Walker TM, Lalor MK, Broda A, et al. Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007–12, with whole pathogen genome sequences: an observational study. Lancet Respir Med 2014; 2: 285–292. 6 Sanchez-Padilla E, Merker M, Beckert P, ...
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ژورنال
عنوان ژورنال: International journal of medical ophthalmology
سال: 2023
ISSN: ['2663-8266', '2663-8274']
DOI: https://doi.org/10.33545/26638266.2023.v5.i1a.131